I'm not really that disappointed, actually.
She said in the letter that "I think your style is terrific, but honestly, I didn't connect with the plot line."
Which is kind of okay with me, because I know the plot is really sort of weird and I know it's going to take someone who likes weird to publish it. Hearing that she liked my style is definitely a plus-- it means that I should work on my other, more normal stories, and see if she'll take one of those.
I have to wait on one more office getting back to me before I send it out again.